Peptide
Thymosin Alpha-1
CAS62304-98-7
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Thymosin alpha-1 is a 28-amino-acid, N-terminally acetylated peptide originally isolated from thymus tissue. Supplied as a lyophilized powder for in-vitro laboratory research. Not for human or veterinary use.
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- Supplied as
- Lyophilized powder in a sealed vial. Bacteriostatic water sold separately.
- Storage
- 2–8 °C refrigerated, or −20 °C for long-term storage. Keep refrigerated after reconstitution.
- Intended use
- Laboratory research only (in vitro). Not for use in humans or animals.
- Delivery
- Dispatched the same business day; shipping calculated at checkout, free on orders of $199.99 or more. US addresses only.
— Product Overview
Description
Thymosin Alpha-1 is the N-terminal segment of a larger protein, prothymosin alpha: residues 2-29 in UniProt entry P06454, with the initiator methionine removed and an acetyl group on the first serine. Its sequence was first determined in 1977 from a calf-thymus extract known as thymosin fraction 5. In one-letter code it reads Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN-OH.
The peptide is strongly acidic: nine of its 28 residues are aspartic acid (3) or glutamic acid (6), against four lysines and no arginine or histidine. Cysteine, methionine and all three aromatic amino acids (tryptophan, tyrosine, phenylalanine) are absent, so its UV absorbance at 280 nm is close to zero. Calculated from its formula, the monoisotopic mass is 3106.50 Da.
Thymosin Alpha-1 comes in one size, a 10mg vial. For research use only. Not for use in humans or animals.
An independent third-party lab tests every batch of Thymosin Alpha-1, and the lab report (COA) is on our COAs page.
— Data sheet
Specifications
Thymosin Alpha-1Research use only
- CAS number
- 62304-98-7
- Molecular formula
- C129H215N33O55
- Molecular weight
- 3108.3 g/mol
- Length
- 28 amino acids
- Vial size
- 10mg
Formula and molecular weight: PubChem (CID 16130571), for the CAS number shown (the free peptide, not a salt form). For laboratory research use only. Not for human or veterinary use.
Research & comparisons
Thymic Peptides in Research: Thymosin Alpha-1, Thymosin Beta-4 and Related Peptides
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Research article · Oct 2026
Thymosin Alpha-1: Mechanism of Action and Research Applications
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Research article · Oct 2026
Thymosin Alpha-1 vs Thymosin Beta-4: Two Unrelated Thymosins, and Where TB-500 Fits
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Head-to-head comparison
Thymosin Alpha-1 vs BPC-157
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Head-to-head comparison
Reconstitution calculator
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Preset for Thymosin Alpha-1
Frequently Asked Questions
What is Thymosin Alpha-1?
Thymosin alpha-1 is a 28-amino-acid, N-terminally acetylated peptide originally isolated from thymus tissue.
Is Thymosin Alpha-1 the same as thymosin beta-4 or TB-500?
No. Thymosin Alpha-1 comes from prothymosin alpha, while thymosin beta-4 is a different protein from a different gene; TB-500 is a seven-residue fragment of thymosin beta-4.
What is it used for?
It is sold for in-vitro laboratory research only. It is not for use in humans or animals and is not intended to diagnose, treat, cure or prevent any disease.
How is it supplied?
As a lyophilized (freeze-dried) powder in a sealed vial. Bacteriostatic water is sold separately.
How should it be stored?
Store the sealed vial at 2–8 °C, or at −20 °C for long-term storage. Keep reconstituted solutions refrigerated.
Is there a lab report (COA) for Thymosin Alpha-1?
Yes. Every batch is tested by an independent third-party lab, and the COA is on our COAs page.
Is this product for human use?
No. It is sold strictly for laboratory research use only and is not for human or veterinary use.
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