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Peptide

PT-141

COA Verified >99% Purity HPLC + MS Tested

Cyclic melanocortin-receptor agonist peptide (bremelanotide) for receptor pharmacology research.

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— Product Overview

Description

PT-141 (bremelanotide) is a synthetic cyclic heptapeptide and analog of alpha-melanocyte-stimulating hormone (α-MSH), developed from the melanotan peptide family. It acts as a melanocortin-receptor agonist with notable activity at MC3R and MC4R, and its cyclic lactam structure gives it greater metabolic stability than linear MSH analogs.


Emerging from melanocortin structure-activity research at the University of Arizona, PT-141 has one of the most thoroughly documented receptor-binding and pharmacokinetic profiles of any research peptide, studied across cell, rodent, and primate models for central melanocortin-pathway activity.


Supplied as a lyophilized powder for laboratory research use only. Not for human consumption.

Frequently Asked Questions

What is PT-141?
PT-141 (bremelanotide) is a synthetic cyclic heptapeptide analog of alpha-MSH that acts as a melanocortin-receptor agonist, with notable activity at MC3R and MC4R.
What is PT-141 studied for in research?
It is studied in cell and animal models for melanocortin-receptor pharmacology and central nervous system signaling, distinct from peripheral vascular-acting compounds.
How is PT-141 different from Melanotan II?
PT-141 is structurally derived from the melanotan peptide family but is a cyclic analog with a different receptor-activity and stability profile.
How is PT-141 supplied?
As a lyophilized powder for laboratory research use only. It is not for human consumption.

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