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Peptide

PT-141

CAS189691-06-3

PT-141 (bremelanotide) is a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH) and a melanocortin-receptor agonist, closely related to Melanotan II. Supplied as a lyophilized powder for in-vitro laboratory research. Not for human or veterinary use.

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Supplied as
Lyophilized powder in a sealed vial. Bacteriostatic water sold separately.
Storage
2–8 °C refrigerated, or −20 °C for long-term storage. Keep refrigerated after reconstitution.
Intended use
Laboratory research only (in vitro). Not for use in humans or animals.
Delivery
Dispatched the same business day; shipping calculated at checkout, free on orders of $149.99 or more. US addresses only.
At a glancePT-141
Intended use
Laboratory research use only (in vitro). Not for human or veterinary use.
Form
Lyophilized (freeze-dried) powder in a sealed vial
Sizes
10mg
Storage
Sealed vial: 2–8 °C, or −20 °C for longer storage. Keep dry and away from light.
Shipping
Ships the same business day when ordered by 3 PM ET (Mon–Sat), with tracking.

Terms on this page

  • COA (Certificate of Analysis): the lab's test report for one batch and size.
  • HPLC (high-performance liquid chromatography): the lab test that measures purity.
  • Mass spectrometry (MS): a lab test that checks the molecule's mass, to confirm identity.
  • Lyophilized: freeze-dried, for a stable powder.
— Product Overview

Description

PT-141 is a cyclic peptide of seven residues. In the sequence shown in the Specifications box, the N-terminal norleucine (Nle, a non-standard amino acid) is acetylated, the phenylalanine is the D-isomer, and the six residues from aspartic acid to lysine form a ring closed by an amide (lactam) bond between the Asp and Lys side chains. The chain ends in a free carboxylic acid.

That C-terminal acid is the only structural difference from Melanotan II, which has the same ring but ends in an amide, and it is why PT-141 is about 1 g/mol heavier. See Melanotan II vs PT-141.

The one size offered is PT-141 10mg, freeze-dried (lyophilized) in a sealed vial. Store vials away from light and divide any reconstituted solution into aliquots before freezing to avoid thawing and refreezing it repeatedly.

For research use only. Not for use in humans or animals.

— Data sheet

Specifications

PT-141Research use only
CAS number
189691-06-3
Molecular formula
C50H68N14O10
Molecular weight
1025.2 g/mol
Sequence
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
Vial size
10mg

Formula and molecular weight: PubChem (CID 9941379), for the CAS number shown (the free peptide, not a salt form). For laboratory research use only. Not for human or veterinary use.

Frequently Asked Questions

What is PT-141?
PT-141 (bremelanotide) is a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH) and a melanocortin-receptor agonist, closely related to Melanotan II.
What is it used for?
It is sold for in-vitro laboratory research only. It is not for use in humans or animals and is not intended to diagnose, treat, cure or prevent any disease.
How is PT-141 different from Melanotan II?
The two cyclic peptides share the same ring sequence; PT-141 ends in a free acid, Melanotan II in an amide.
How is it supplied?
As a lyophilized (freeze-dried) powder in a sealed vial. Bacteriostatic water is sold separately.
How should it be stored?
Store the sealed vial at 2–8 °C, or at −20 °C for long-term storage. Keep reconstituted solutions refrigerated.
Is this product for human use?
No. It is sold strictly for laboratory research use only and is not for human or veterinary use.
Where is the COA for PT-141?
Published lab reports are listed on the COAs page; the report for this product is added there when it is published.
When will my order ship?
Orders placed by 3 PM ET, Monday to Saturday, ship the same business day with tracking. Options and prices are on the Shipping Policy page.

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