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Peptide

Epithalon

CAS307297-39-8

Epithalon (also spelled Epitalon) is the synthetic tetrapeptide Ala-Glu-Asp-Gly (AEDG). Supplied as a lyophilized powder for in-vitro laboratory research. Not for human or veterinary use.

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Supplied as
Lyophilized powder in a sealed vial. Bacteriostatic water sold separately.
Storage
2–8 °C refrigerated, or −20 °C for long-term storage. Keep refrigerated after reconstitution.
Intended use
Laboratory research only (in vitro). Not for use in humans or animals.
Delivery
Dispatched the same business day; shipping calculated at checkout, free on orders of $149.99 or more. US addresses only.
At a glanceEpithalon
Intended use
Laboratory research use only (in vitro). Not for human or veterinary use.
Form
Lyophilized (freeze-dried) powder in a sealed vial
Sizes
10mg
Storage
Sealed vial: 2–8 °C, or −20 °C for longer storage. Keep dry and away from light.
Shipping
Ships the same business day when ordered by 3 PM ET (Mon–Sat), with tracking.
More details: COA by size, terms, further reading

Terms on this page

  • COA (Certificate of Analysis): the lab's test report for one batch and size.
  • HPLC (high-performance liquid chromatography): the lab test that measures purity.
  • Mass spectrometry (MS): a lab test that checks the molecule's mass, to confirm identity.
  • Lyophilized: freeze-dried, for a stable powder.
— Product Overview

Description

Epithalon is also written Epitalon or Epithalone, and is often referred to by its one-letter sequence, AEDG. It was designed from the amino-acid composition of epithalamin, a bovine pineal gland extract; Epithalon itself is one defined synthetic sequence, not an extract.

Chemically it is a very small, acidic peptide. Glutamate and aspartate both carry acidic side chains; with the free C-terminal carboxyl and the single N-terminal amine, the net charge is about −2 at neutral pH. PubChem computes an XLogP3 of −5.5, which marks it as strongly hydrophilic. It has no tryptophan or tyrosine, so it cannot be quantified by UV absorbance at 280 nm, and no sulfur-containing residues (cysteine or methionine).

In an Epithalon 10mg vial, the labeled 10 mg is about 25.6 µmol, calculated from its molar mass. For laboratory research use only; not for use in humans or animals.

— Data sheet

Specifications

EpithalonResearch use only
CAS number
307297-39-8
Molecular formula
C14H22N4O9
Molecular weight
390.35 g/mol
Sequence
H-Ala-Glu-Asp-Gly-OH
Vial size
10mg

Formula and molecular weight: PubChem (CID 219042), for the CAS number shown (the free peptide, not a salt form). For laboratory research use only. Not for human or veterinary use.

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Frequently Asked Questions

What is Epithalon?
Epithalon (also spelled Epitalon) is the synthetic tetrapeptide Ala-Glu-Asp-Gly (AEDG).
What is it used for?
It is sold for in-vitro laboratory research only. It is not for use in humans or animals and is not intended to diagnose, treat, cure or prevent any disease.
Is Epithalon the same as Epitalon?
Yes. Epithalon and Epitalon are two transliterations of the same compound.
Is Epithalon the same as epithalamin?
No. Some chemical databases list the names as synonyms, but epithalamin is an extract of the bovine pineal gland, while Epithalon is a single synthetic tetrapeptide, Ala-Glu-Asp-Gly.
How is it supplied?
As a lyophilized (freeze-dried) powder in a sealed vial. Bacteriostatic water is sold separately.
How should it be stored?
Store the sealed vial at 2–8 °C, or at −20 °C for long-term storage. Keep reconstituted solutions refrigerated.
Is this product for human use?
No. It is sold strictly for laboratory research use only and is not for human or veterinary use.
Where is the COA for Epithalon?
Published lab reports are listed on the COAs page; the report for this product is added there when it is published.
When will my order ship?
Orders placed by 3 PM ET, Monday to Saturday, ship the same business day with tracking. Options and prices are on the Shipping Policy page.

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