DSIP
CAS62568-57-4
DSIP (delta sleep-inducing peptide) is a nine-amino-acid peptide, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE), first isolated in the 1970s. Supplied as a lyophilized powder for in-vitro laboratory research. Not for human or veterinary use.
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- Supplied as
- Lyophilized powder in a sealed vial. Bacteriostatic water sold separately.
- Storage
- 2–8 °C refrigerated, or −20 °C for long-term storage. Keep refrigerated after reconstitution.
- Intended use
- Laboratory research only (in vitro). Not for use in humans or animals.
- Delivery
- Dispatched the same business day; shipping calculated at checkout, free on orders of $149.99 or more. US addresses only.
- Intended use
- Laboratory research use only (in vitro). Not for human or veterinary use.
- Form
- Lyophilized (freeze-dried) powder in a sealed vial
- Sizes
- 10mg
- Storage
- Sealed vial: 2–8 °C, or −20 °C for longer storage. Keep dry and away from light.
- Shipping
- Ships the same business day when ordered by 3 PM ET (Mon–Sat), with tracking.
More details: COA by size, terms, further reading
Terms on this page
- COA (Certificate of Analysis): the lab's test report for one batch and size.
- HPLC (high-performance liquid chromatography): the lab test that measures purity.
- Mass spectrometry (MS): a lab test that checks the molecule's mass, to confirm identity.
- Lyophilized: freeze-dried, for a stable powder.
Description
DSIP is the common name; emideltide is its International Nonproprietary Name (INN). Its isolation and amino-acid sequence were reported in 1977 by G. A. Schoenenberger and M. Monnier in the Proceedings of the National Academy of Sciences.
The sequence is glycine-rich: three of the nine residues are glycine and two are alanine. Its only aromatic residue is the N-terminal tryptophan, so DSIP solutions absorb UV light at 280 nm and can be quantified that way. There is no cysteine, so the peptide has no disulfide bonds. Aspartate, glutamate and the free C-terminal acid outweigh the single N-terminal amine, giving a net charge of about −2 at neutral pH.
By molar mass, the labeled 10 mg of a DSIP 10mg vial is about 11.8 µmol. For laboratory research use only; not for use in humans or animals.
Specifications
- CAS number
- 62568-57-4
- Molecular formula
- C35H48N10O15
- Molecular weight
- 848.8 g/mol
- Sequence
- H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH
- Vial size
- 10mg
Formula and molecular weight: PubChem (CID 68816), for the CAS number shown (the free peptide, not a salt form). For laboratory research use only. Not for human or veterinary use.
Frequently Asked Questions
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