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Peptide

DSIP

CAS62568-57-4

DSIP (delta sleep-inducing peptide) is a nine-amino-acid peptide, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE), first isolated in the 1970s. Supplied as a lyophilized powder for in-vitro laboratory research. Not for human or veterinary use.

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Supplied as
Lyophilized powder in a sealed vial. Bacteriostatic water sold separately.
Storage
2–8 °C refrigerated, or −20 °C for long-term storage. Keep refrigerated after reconstitution.
Intended use
Laboratory research only (in vitro). Not for use in humans or animals.
Delivery
Dispatched the same business day; shipping calculated at checkout, free on orders of $149.99 or more. US addresses only.
At a glanceDSIP
Intended use
Laboratory research use only (in vitro). Not for human or veterinary use.
Form
Lyophilized (freeze-dried) powder in a sealed vial
Sizes
10mg
Storage
Sealed vial: 2–8 °C, or −20 °C for longer storage. Keep dry and away from light.
Shipping
Ships the same business day when ordered by 3 PM ET (Mon–Sat), with tracking.
More details: COA by size, terms, further reading

Terms on this page

  • COA (Certificate of Analysis): the lab's test report for one batch and size.
  • HPLC (high-performance liquid chromatography): the lab test that measures purity.
  • Mass spectrometry (MS): a lab test that checks the molecule's mass, to confirm identity.
  • Lyophilized: freeze-dried, for a stable powder.
— Product Overview

Description

DSIP is the common name; emideltide is its International Nonproprietary Name (INN). Its isolation and amino-acid sequence were reported in 1977 by G. A. Schoenenberger and M. Monnier in the Proceedings of the National Academy of Sciences.

The sequence is glycine-rich: three of the nine residues are glycine and two are alanine. Its only aromatic residue is the N-terminal tryptophan, so DSIP solutions absorb UV light at 280 nm and can be quantified that way. There is no cysteine, so the peptide has no disulfide bonds. Aspartate, glutamate and the free C-terminal acid outweigh the single N-terminal amine, giving a net charge of about −2 at neutral pH.

By molar mass, the labeled 10 mg of a DSIP 10mg vial is about 11.8 µmol. For laboratory research use only; not for use in humans or animals.

— Data sheet

Specifications

DSIPResearch use only
CAS number
62568-57-4
Molecular formula
C35H48N10O15
Molecular weight
848.8 g/mol
Sequence
H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH
Vial size
10mg

Formula and molecular weight: PubChem (CID 68816), for the CAS number shown (the free peptide, not a salt form). For laboratory research use only. Not for human or veterinary use.

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Frequently Asked Questions

What is DSIP?
DSIP (delta sleep-inducing peptide) is a nine-amino-acid peptide, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE), first isolated in the 1970s.
What is it used for?
It is sold for in-vitro laboratory research only. It is not for use in humans or animals and is not intended to diagnose, treat, cure or prevent any disease.
What is the amino acid sequence of DSIP?
Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE), nine amino acids.
Is DSIP the same as emideltide?
Yes. Emideltide is the International Nonproprietary Name (INN) for DSIP, the nonapeptide Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu.
How is it supplied?
As a lyophilized (freeze-dried) powder in a sealed vial. Bacteriostatic water is sold separately.
How should it be stored?
Store the sealed vial at 2–8 °C, or at −20 °C for long-term storage. Keep reconstituted solutions refrigerated.
Is this product for human use?
No. It is sold strictly for laboratory research use only and is not for human or veterinary use.
Where is the COA for DSIP?
Published lab reports are listed on the COAs page; the report for this product is added there when it is published.
When will my order ship?
Orders placed by 3 PM ET, Monday to Saturday, ship the same business day with tracking. Options and prices are on the Shipping Policy page.

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